Our DS did fine on vacation too. His first vacation was all the way from the UK to South Africa with an 11 hour plane ride. We were dreading it, and he took it in his stride. I would just say that you try to stick to your routine as best you can, of course there are going to be days when this is not going to be so easy, and there is going to be AP involved, but you can always try and get that sorted the next day.
With regards to the needles. We gave our DS some Calpol when he has his first set as he seemed very grizzly. This did help him settle down a bit more.
Could you post your routine for us, with your current E, A, windown routine and S so that we can see if we can try and help you out with the short naps?
Hope that she settled well for you last night and that she is feeling a bit better today.
Paula