I agree with pps about giving as much support as needed and any kind of AP that works when they are poorly and also agree chances are they'll let you know they don't need you any more once the illness has passed.
My DS was very poorly at 10, almost 11 months. He hadn't had a night feed in ages but during the illness and his recovery from the illness he needed to feed at night. He'd actually been admitted to hospital for 4 days as it was worse than a regular cold. The night feeds never became a habit, he really did need them, and when he didn't he just stopped.
For snot and breathing it can help to elevate the cot mattress at the head end. If you have a cot wedge use it, or cot blocks. If not then a pillow placed underneath the mattress (to maintain a smooth sleeping surface and avoid possibility of suffocation from a pillow) can help to raise that end, this can really help with keeping the nose and airway clear. They raise the mattress in hospital this way if they are not in a cot that has a split raised section.
I had no luck ever with a nasal aspirator. I do find that massaging the nostrils (1 at a time) in a downward motion brings a good amount of snot out, lubricate with a little moisturiser cream or oil on the outside of the nose and gently squeeze and massage down until the bogies are out.
In case you don't know, you can double up on meds giving paracetamol and ibuprofen so long as you don't go over the max amount of either. it can be helpful with bad colds and fever to be able to give one then the other a couple of hours later. I find it helps to write it down so you know exactly what time you gave what (sleep deprivation does not make remembering easy!). If LO will take it you can also try a dream meds with a syringe when you go to bed (if you time the doses) which might help her get through the night.
Hope she's feeling better soon!