Hi louisa, I'm trying to find out more about aspartame from a sals perspective. DD's PPI is Prevacid for her reflux which has aspartame in it. I'm not sure if it is having an effect on her but she seems to have her worst symptoms after she has it morning and night. I asked Eloise if she knew anything and I think she is checking with others in her local forum who might know. Will let you know what I find out.