My LO is cutting his first also... I have wondered the exact same things, so I will be interested to hear what others would say... I bought an herbal teething liquid. It seems to help, but maybe not quite as much as the Tylenol. I also got some Orajel to rub on the gum. I do hate to use meds. But I also don't want him to suffer. Our doctor suggested teething tablets, so when I went to Walgreens, I looked, and this teething liquid is basically the same. It's all natural... chamomile and things like that. I don't like giving him anything, though. But I do b/c I don't want him to hurt. Oh, and one of the moderators said Motrin lasts longer than Tylenol. I think she said it works better too.