DS1 with no reflux (but spirited) was difficult to settle initially,and sometimes, as a newborn, before we had him on a routine, would be awake all day
.
But the not falling asleep on boob, car stroller sounds ominously like DS2, with reflux. He cried in the stroller and had to be picked up, he cried in the car, until I stopped the car (who knows why?) and the breast just made him cry and spit up.
So, I'm not sure which, if either, your DD is, but DS1 was far easier to sort, so I hope it's not reflux.