No there is not since it is pasteurized. The only caution is the sugar consumption.
Try to buy organic/pure Grade A maple syrup... so no added sugars, corn syrup, high fructose, additives etc... a lot of the cheapo brands are actually corn syrup and food colouring!
We always use it and/or honey...much better for you than sugar. I often drink hot water, lemon and maple syrup...yummm. We get ours fresh form the maple sugar bush near by as we are in Canada.
HTH,
Ais x