Oh, mama. I am sorry, I had a bad sleeper while pregnant about 15 months ago and it was terrifying. Though, to be honest, what I imagined was far worse than what actually happened and you have plenty of time to get this straightened out!
I also have a 3yo with night wakings and who I have definitely noticed has jumpy legs (as I call them because I also have them, and my mom before me!) I didn't know that anemia could lead to restless legs. My son had anemia about 18 months ago and I wonder if it has returned. He is a terrible eater so I suppose it is possible.
I don't have a ton of good advice but if she is waking up on a schedule I have used Wake to Sleep succesfully with my son and think it would work for that 1230 wakeup. You could try sneaking in at midnight and just gently waking her or even getting her to stir a bit so her schedule is off. I am a firm believer in the technique because, like I said, it has worked for me. For my son though, I couldn't wake him all the way or do a diaper change as some have suggested in other posts. I just stuck to the gentlest touches. If you disturb that first waking, the others *might* fall away. Or! They might start up on a later schedule and then you can implement the technique again later. When it worked for us, I think it was usually effective by the third day.