Trish~ Hey. I'm no expert... but YES I think it COULD be the soy. My sister has a baby who is almost 5 months, and I have a 5 month old baby. Her son has tried soy due to exema, and struggled with constipation pretty badly. My son was quite gassy until about a month ago, when I started solids... we were breast feeding until this week. I used Mylocon instead of Gripe Water (which we tried too.) I feel so bad for your daughter. It sounds like she is in pain. Can you imagine? Can you see a pattern at all, in regards to her waking? You may start to chart it for a while, to see if a pattern is developing. If you know how long after she eats, it takes for her to start to struggle... maybe you can at least be more prepared to help her, or shift feeding her, etc. ? I don't know. We use GentleEASE Lipil from Enfamil, this has also helped with his gas and spitting up. I wish I could be more of a help. I know its frustrating. My son has really had a hard time with night wakings as well (for different reasons.) Good luck, Lori