I agree with vicki that it is worth trying some of the less invasive options to see if they help at all - I saw an improvement in sleep with e and x when we cut out dairy, and it did happen pretty quickly. Also, x has been on the most ridiculously low dose of reflux meds for ages and we tried to wean last week and his sleep deteriorated - no obvious discomfort, just not sleeping. I can't imagine that what he is having can possibly make any difference, but it clearly does.